Depart by bus for Guyana, crossing the newly-constructed (2009) Takutu River Bridge. Brazil drives on the right and Guyana on the left, and there's a nifty little crossover bridge to cope with this idiosyncrasy.
Continue north into the Iwokrama, with stops in the forest along the way. Jaguars, jaguarundi, tayras, as well as striking bird life, including the coq of the rock, and the harpy eagle, are often seen among the trees. Spend the night at the Atta Camp, a block of eight small cabins. From here there is access to a fantastic canopy walkway, built out from a steep escarpment, which gives access to the creatures of the forest.